Welcome to the Truman Lab at UNC Charlotte!
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We are interested in the basic question of how molecular chaperones such as Hsp70 and Hsp90 are modified in cancer. Understanding these modifications (known as the “Chaperone Code”) will allow us to design novel anticancer therapies.
What does Hsp70 do in cells?
The lab incorporates protein biochemistry, molecular biology, proteomics, systems biology, bacterial and yeast genetics and cell culture technologies.
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Keywords: protein-protein interactions, protein folding, CRISPR-CAS9, cancer, signal transduction, phosphorylation, Hsp70, Hsp90, cell cycle, DNA damage response, yeast genetics.
Interested in working with CRISPR-CAS9?
Our lab utilizes CRISPR to knockout, mutate and epitope tag genes. If you are interested in collaborating on a CRISPR project, please click here for more details!
Genome Integrity Group Meetings
We host a monthly meeting with other labs who study DNA damage, genome integrity and cancer. For more information, please click here.
NIH-funded research opportunities for postdocs, graduate and undergraduate students available!
For more information, please click here.